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In Greece, bloodletting was in use in the fifth century BC during the lifetime of Hippocrates , who mentions this practice but generally relied on dietary techniques . [10] Erasistratus , however, theorized that many diseases were caused by plethoras, or overabundances, in the blood and advised that these plethoras be treated, initially, by exercise , sweating , reduced food intake, and vomiting. [11] Herophilus advocated bloodletting. Archagathus , one of the first Greek physicians to practice in Rome , also believed in the value of bloodletting.


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